CYTOTREXATE 10MG TAB 10S
Generics
Methotrexate
Used For
Cancer
How it works
Methotrexate is a cytostatic that inhibits cell growth. Methotrexate has its greatest effect on cells which increase frequently like cancer cells, bone marrow cells and skin cells.
Usage And Safety
Dosage
Adults : Antineoplastic : Burkitt's Lymphoma : Stages I-II : Orally 10-25mg/day for 4-8 day for several courses ; separate by 7-10 day rest period . Lymphosarcomas : Stage III : Orally : 0.625-2.5mg/kg/day. Leukaemia : Induction : 3.3mg/m2 with prednisolone every day. Remission maintenance : 15mg/m2 Orally/IM twice weekly or 2.5mg/kg IV every 14 day. Children : Meningeal leukaemias : Intrathecal : Dilute preservative free methotraxate to 1mg/ml. Dose every 2-5 day . >3yr : 12mg . 2 yr : 10mg. 1yr : 8mg . <1yr : 6mg. Juvenile rheumatoid arthritis : Children : 2-16 yr : 10mg/m2 once weekly. Adjust dose to optimal response. OR As directed by your physician.