SITA MET TABLET 50MG 1000MG 14S
Sita Met 50 mg / 1000 mg Tablets (14s)—ideal for pharmacy listings, e-commerce catalogs, or diabetes care websites:
Sita Met 50 mg / 1000 mg Tablet (14s) – Sitagliptin + Metformin Extended‑Release
Overview
Sita Met combines Sitagliptin 50 mg (DPP‑4 inhibitor) with Metformin Hydrochloride 1000 mg ER (biguanide) in a fixed‑dose tablet. This dual‑action therapy is prescribed for type 2 diabetes mellitus when monotherapy is inadequate, helping control blood sugar levels effectively
Key Benefits & Mechanism
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Improves glycemic control by lowering fasting and post‑mealtime blood glucose
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Sitagliptin increases incretin hormones—GLP‑1 and GIP—to enhance insulin secretion and suppress glucagon
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Metformin ER reduces hepatic glucose production, increases insulin sensitivity, and slows intestinal glucose absorption
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Convenient twice‑daily dosing with meals improves compliance and minimizes GI side effects
Common Uses
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As adjunct therapy to diet and exercise in adults with type 2 diabetes inadequately controlled on either component alone
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Used when adding sitagliptin and metformin separately is clinically appropriate
Dosage & Administration
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Typically 1 tablet twice daily with meals, or as directed by physician
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Total daily dose usually not to exceed 100 mg sitagliptin and 2000 mg metformin
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For patients already on metformin, sitagliptin is added without exceeding safe dosing levels
Safety, Contraindications & Precautions
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Contraindicated in severe renal impairment (eGFR < 30 mL/min/1.73 m²) and not recommended if eGFR is 30–45 unless benefits justify use Avoid in liver disease, acute or chronic metabolic acidosis, or diabetic ketoacidosis
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Possible adverse effects: diarrhea, nausea, headache, upper respiratory infections, hypoglycemia, vitamin B₁₂ deficiency, rare lactic acidosis, pancreatitis, or serious allergic reactions
📦 Packaging & Availability in Pakistan
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Supplied as 14 film-coated tablets per pack; sold as 2×7 or 14‑count strips
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Marketed by CCL Pharmaceuticals; average retail price around PKR 580–650 per pack depending on vendor and discounts