XENGLU MET 12.5 500MG TAB 28s

Here’s a detailed overview of Xenglu‑Met 12.5 mg / 500 mg tablets (28‑count) — a fixed‑dose combination of empagliflozin 12.5 mg and metformin 500 mg, manufactured by Hilton Pharmaceuticals (Pvt.) Ltd, Pakistan Drugs.com+15Sehat+15healthwire.pk+15.

 What It Is & How It Works

• Empagliflozin (SGLT‑2 inhibitor): Promotes urinary glucose excretion to reduce blood sugar.

• Metformin (biguanide): Lowers hepatic glucose production and improves insulin sensitivityIndication: Adjunct to diet and exercise for adults with type 2 diabetes not adequately controlled on metformin or empagliflozin alone, or already on both separately

Benefits

• Enhanced glycemic control through dual mechanisms addressing both insulin resistance and renal glucose reabsorption

• Weight-friendly: Empagliflozin can contribute to modest weight loss via glucosuria.

• Cardiorenal protection: Empagliflozin linked to reduced hospitalizations for heart failure and slower progression of kidney disease in type 2 diabetics at risk 

• Simplified regimen: Combines two medications into one convenient daily tablet to improve adherence

 Dosage & Administration

Standard dose: 1 tablet once daily, preferably with a meal. May be split into twice‑daily doses based on total metformin load, health status, and tolerability 

• Dose adjustments: Gradual upward titration allowed to maximum empagliflozin 25 mg/day and metformin 2000 mg/day Duration: Long-term use is common; consistent monitoring needed

 Common Side Effects

• Gastrointestinal: Nausea, diarrhea, abdominal discomfort, loss of appetite, metallic taste.

• Genitourinary: Urinary tract infections, genital yeast infections, frequent urination.

• Other: Headache, dizziness, upper respiratory symptoms, mild hypoglycemia (typically when used with insulin or secretagogues)